Cirrhosis Of Liver
Cirrhosis Of Liver: It is shrinkage and fibrosis of liver; it shows end stage of liver failure. In Cirrhotic, liver normal parenchyma is replaced by fibrous tissue, which cannot do normal functions resulting in liver failure.
Liver cirrhosis is secondary to various diseases; it is very dangerous and discomforting state. Because liver is the main organ which detoxifies toxins, produce antibodies and metabolize most food particles because of cirrhosis these functions cannot be done and person predisposed to many problems.
Causes: Infection with hepatitis viruses B and C are major causes of cirrhosis. Alcohol abuse is anther cause; various metabolic diseases can also cause cirrhosis like Wilson’s disease. Chronic iron overload as occurs in hereditary hemo chromatists is another cause. Obesity, hepatic toxic substances, long-term corticosteroid therapy, glycogen storage diseases and lipid storage diseases all cause cirrhosis.
Symptoms: In early stages patient is asymptomatic, then if diseases progresses and liver stops functioning, various symptoms occur including loss of appetite, weight loss, jaundice or yellow discoloration of skin, black stool, rectal bleeding, indigestion, vomiting, swelling of abdomen sometimes huge to cause shortness of breath, this swelling is called ascites, clubbing of fingers, bruises on skin, infections, anemia, renal failure secondary to liver failure resulting initially in increased urination then decreased urine output , bone pain.
Other complications are confusion and coma, esophageal varies, constipation and ascites resulting in severe dyspepsia and cardiac failure.
Diagnosis: Method of diagnosis is liver biopsy. It gives the exact clue of liver fibrosis, ultrasound abdomen and CT scan are also used to detect complications like ascites, and endoscopy is required to detect esophageal varies.
Treatment: In initial stages supportive treatment is needed like drainage of ascites, banding of esophageal varies, prevention of constipation and coma by laxatives. Moreover, symptomatic treatment. Final treatment of end stage disease is liver transplant.
In this page, we are going to discuss about Cirrhosis Of Liver and symptoms, diagnosis and treatment in Urdu and Roman Hindi for the people of Pakistan and India.